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Steroid xenobiotic receptor

Zhou C, Assem M, Tay JC, et al. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest 2006 116(6) 1703-1712. [Pg.504]

Zhou C, Tabb MM, Sadatrafiei A, et al. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metab Dispos 2004 32(10) 1075-1082. [Pg.504]

SXR Steroid end xenobiotics receptor (human] CAR Constitutive active (androstane) receptor other UGT substrates... [Pg.241]

Takeshita A, Koibuchi N, Oka J, et al. Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription. Eur J Endocrinol 2001 145 513-17. [Pg.376]

Most of the research on xenobiotic receptors has been conducted in mammalian systems. These studies have identified three families of proteins as having important roles in regulating the response to xenobiotic chemicals (Table 1). The aryl hydrocarbon receptor (AHR), a member of the basic helix-loop-helix Per-ARNT-Sim (bHLH-PAS) family of transcription factors, is well known for its role in the altered gene expression and toxicity elicited by chlorinated dioxins and related planar halogenated aromatic hydrocarbons (PHAHs) as well as certain polynuclear aromatic hydrocarbons (PAHs)114 188 244. Several members of the nuclear/steroid... [Pg.192]

Zhou, C., Tabb, M. M., Nelson, E. L., Grun, E, Verma, S., Sadatrafiei, A., Lin, M., Mallick, S., Forman, B. M., Thummel, K. E., et al. (2006) Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J. Clin. Invest. 116, 2280-2289. [Pg.58]

Ichikawa, T., Horie-Inoue, K., Ikeda, K., Blumberg, B., and Inoue, S. (2006) Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J. Biol. Chem. 281, 16927-16934. [Pg.142]

N., Blumberg, B., and Sasano, H. (2006) Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res. 66, 535-542. [Pg.143]

Takeshita, A., Taguchi, M., Koibuchi, N., and Ozawa, Y. (2002) Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics. J. Biol. Chem. 277, 32453-32458. [Pg.180]

See other pages where Steroid xenobiotic receptor is mentioned: [Pg.1388]    [Pg.71]    [Pg.150]    [Pg.181]    [Pg.1388]    [Pg.71]    [Pg.150]    [Pg.181]    [Pg.7]    [Pg.470]    [Pg.293]    [Pg.295]    [Pg.310]    [Pg.306]    [Pg.222]    [Pg.242]    [Pg.399]    [Pg.7]    [Pg.1945]    [Pg.323]    [Pg.72]    [Pg.79]    [Pg.315]    [Pg.335]    [Pg.340]    [Pg.511]    [Pg.453]    [Pg.178]    [Pg.50]    [Pg.145]    [Pg.241]    [Pg.270]    [Pg.349]   
See also in sourсe #XX -- [ Pg.181 ]



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Steroid and xenobiotic receptor

Xenobiotic receptors

Xenobiotics receptors

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