Steroid protein activity index

One of the best efforts to compare the anabolic activity of many steroids which have been discussed is that of Albanese and coworkers (1), who devised a careful means of comparing a wide series of steroids. They employed nitrogen balance studies in appropriate patients. They then expressed the steroid protein activity index, the SPAI, on a comparative basis. The antianabolic or catabolic adrenal cortical steroids all have negative values by this assay. Table II shows comparative SPATs of seven of the steroids which have been discussed. It can be seen by this index that testosterone propionate is the least active and stanozolol the most active. Further reports from Albanese and coworkers will be anticipated with interest. 

TABLE II. Steroid Protein Activity Index (SPAI) of Anabolic Steroids in Patients(f)... 

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