Sprague

Golab J T, Sprague J R, Oarron K T, Schatz G 0 and Van Duyne R P 1988 A surface enhanced hyper-Raman scattering study of pyridine adsorbed onto silver experiment and theory J. Chem. Phys. 88 7942-51... 

D, J Greene, A Smellie and P Sprague 1996. Identification of Common Functional ifigurations among Molecules. Journal of Chemical Information and Computer Science 36 563-571. 

S Kahn, H Savoj, P Sprague and S Teig 1994, Chemical Function Queries for 3D Database ch. Journal of Chemical Information and Computer Science 34 1297-1308. 

These subjects have been reviewed up the year 1975 in various works. Prij s Card Index (363) of thiazole compounds provides swift access to information on individual compounds. Syntheses of thiazoles have been carefully reviewed by Wiley etal. (361), and in 1957 the subject was dealt with in an excellent survey by Sprague and Land (448). 

As already noted by Sprague and Land (46), no accurate data are available for 2-thiazolecarboxylic acid, but it appears to be a considerably stronger acid than either 4- or 5-thiazolecarboxylic acid (7). It is difficult to study experimentally the acidity of these compounds because of their amphoteric character. 

Reductions carried out with lithium aluminium hydride are not always so successful. As noted by Sprague (46) the esters of 2-aminothiazole carboxylic acids behave somewhat differently with AlLiH4 (55). 

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