Speciated isotope dilution mass spectrometry chemical speciation

Isotope dilution mass spectrometry is an accurate and sensitive technique for determining toxic trace elements in food matrices. Lead, cadmium, and thallium have been analyzed rapidly down to very low levels by ICP-MS. The latter technique is particularly useful for simultaneous measurement of a wide range of elements. Because the toxicity of an element can be highly dependent on its chemical form, ICP-MS is also useful in the speciation of toxic minerals in foodstuffs by combination with HPLC or SEC. [Pg.2933]

Chapter 8 provides the reader with the basic principles of isotope dilution mass spectrometry used for elemental analysis and also discusses more advanced features of this calibration approach, such as its use in direct solid sample analysis and in elemental speciation work, wherein not the total amount but that of various chemical species of a target element need to be determined. [Pg.546]

See also Analytical Reagents Purification. Arsenic. Atomic Absorption Spectrometry Electrotfiermal. Atomic Mass Spectrometry Inductively Coupled Plasma. Dioxins. Elemental Speciation Oven/iew. Endocrine Disrupting Chemicals. Geochemistry Sediment. Humic and Fulvic Compounds. Isotope Dilution Analysis. Mass... [Pg.1999]