Speciated isotope dilution mass spectrometry analytics

Encinar, J. R., Schaumloffel, D., Ogra, Y., and Lobinski, R., Determination of selenomethionine and selenocysteine in human serum using speciated isotope dilution-capillary HPLC-inductively coupled plasma collision cell mass spectrometry, Analytical Chemistry 76(22), 6635-6642, 2004. [Pg.96]

The principle of the isotope dilution analysis (IDA) is described in Section 6.4. Due to its advantages as a definitive and accurate analytical method for the determination of element concentration via isotope ratio measurements, IDA is being increasingly applied in mass spectrometry, especially in ICP-MS and LA-ICP-MS as one of the most frequently used techniques. For example, the isotope dilution technique is employed in species analysis in biological systems, " e.g., for the determination of mercury species in tuna material,or in aquatic systems. Further applications of the isotope dilution technique are the determination of selenomethionine in human blood serum by capillary HPLC-ICP (ORC) MS ° or sulfur speciation in gas oil, diesel or heating fuel by LA-ICP-MS. Evans and co-workers have reported on the high accuracy analysis of sulfur in diesel fuel by IDA. ICP-SFMS has been employed for Si species analysis in biological or clinical samples and... [Pg.239]

See also Analytical Reagents Purification. Arsenic. Atomic Absorption Spectrometry Electrotfiermal. Atomic Mass Spectrometry Inductively Coupled Plasma. Dioxins. Elemental Speciation Oven/iew. Endocrine Disrupting Chemicals. Geochemistry Sediment. Humic and Fulvic Compounds. Isotope Dilution Analysis. Mass... [Pg.1999]

See also Atomic Absorption Spectrometry Interferences and Background Correction. Atomic Emission Spectrometry Principles and Instrumentation Interferences and Background Correction Flame Photometry Inductively Coupled Plasma Microwave-Induced Plasma. Atomic Mass Spectrometry Inductively Coupled Plasma Laser Microprobe. Countercurrent Chromatography Solvent Extraction with a Helical Column. Derivatization of Analytes. Elemental Speciation Overview Practicalities and Instrumentation. Extraction Solvent Extraction Principles Solvent Extraction Multistage Countercurrent Distribution Microwave-Assisted Solvent Extraction Pressurized Fluid Extraction Solid-Phase Extraction Solid-Phase Microextraction. Gas Chromatography Ovenriew. Isotope Dilution Analysis. Liquid Chromatography Ovenriew. [Pg.4847]