Soft tissue engineering functional scaffoldings

This improved ability to design peptide-based fibers from the bottom up should pave the way to real-life applications of such materials in bionanotechnology, particularly with regard to templating inorganic and other functional materials, and as soft biomimetic scaffolds in 3D cell culture and tissue engineering. 

Abstract Molecular self-assembly is a powerful approach being explored for novel supra-molecular nanostructures and bio-inspired nanomaterials. In this article, we focus on recent research concerning the self-assembly of de novo designed artificial peptides and peptidomimetics into nanofiber structures, specifically towards developing a new class of soft-materials. These nanofiber architectures have potential use not only in biomedical applications, such as 3D-matrix scaffolds for tissue engineering and biomineralization, but also in nanotechnology such as nano-templates and dimension-regulated functional nano-objects. 

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