Sodium hydroxide soln

Crystals, mp 162-166. Freely sol in acetone, ether, ethanol, methanol and dil sodium hydroxide soln sol in vegetable oils moderately so] in glacial acetic acid slightly sol in benzene, chloroform, petr ether, and dil ethanol practically insot in wafer and in dil mineral acids. Neutral to litmus in 75% ale soln. 

Almost black, thick liq or semisolid characteristic odor. A small portion of coal tar dissolves in water all or almost all dissolves in benzene or nitrobenzene partly dissolves in alcohol, ether, chloroform, carbon disulfide, methanol, acetone, petr ether, or sodium hydroxide soln. Practically insol in water, Sol in 20 parts alcohol miscible with abs alcohol, acetone, patrolatum, oils and fats. 

Trihydrate, prisms and leaflets from water, mp 176 with decompn, when anhydr. Soluble in about 1200 parts cold water more so] in hot water sol in alcohol, in sodium hydroxide soln insol in ether. 

Br 77.65%, Na 22.35%. NaBr. Prepd commercially by adding some excess bromine to a sodium hydroxide soln forming a mixture of bromide and bromate. The reaction products are evaporated to dryness and treated with carbon to reduce the bromate to bromide. Ref van ter Meulen, U.S. pat. 1,775,598 (1930) Robertson, Ind, Eng. Chem. 34, 133 (1942) T O. Some, C O. Wilson, Roger s Inorganic Pharmaceutical Chemistry (Lea Sl Febiger, Philadelphia, 8th ed., 1967) pp 213-216. 

White or slightly gray powder, d 6.95. Insol in water, alcohol, or cold acids slowly sol in hot coned potassium or sodium hydroxide soln. 

Dihydrate, crystals absorbs oxygen From air and forms insol oxychloride, d 2.71. mp 37-38 when rapidly heated dec on strong heating. Sol in less than its own wt of water with much water it Forms an insol basic salt very sol in dil or in coned hydrochloric acid also sol in alcohol, ethyl acetate, glacial acetic acid, sodium hydroxide soln. Keep tightly closed, in a cool place. 

Viscose, A viscous orange-red aq soln of sodium cellulose xanthogenate obtained by dissolving wood pulp cellulose in sodium hydroxide soln and treating with carbon disulfide. Manuf Bachlott, LI.S. pat. 2,855,321 (1958 to du Pont) Von Kohorn, U.S. pat. 2,985,647 (1961). 

The antibiotics were visualized as dark brown spots after spraying with a silver nitrate soln. followed by 5% sodium hydroxide soln. 

Ethyl acetate-butanol- 3 M phosphate buffer of pH 5.3 (80 20 100, v/v) the pH is kept at 5.3 with N sodium hydroxide soln. 

---