Sodium dodecanoate

Sodium dodecanoate (sodium laurate) [629-25-4] M 222.3, pK 5.3 (-COOH). Neutralised by adding a slight excess of dodecanoic acid, removing it by ether extraction. The salt is recrystd from aq soln by adding pure Me2CO and repeating the process (see sodium decanoate on p. 468). Also recrystd from MeOH. 

Sierra, M.B., Morini, M.A., Schulz, P.C., Junquera, E. and Aicart, E. (2007) Effect of double bonds in the formation of sodium dodecanoate and sodiumlO-undecenoate mixed micelles in water. Journal of Physical Chemistry B, 111 (40), 11692-11699. 

E. coli A. caviae phaC and phaj P(3HB-co-3HHx) Sodium dodecanoate 71... 

Another anionic surfactant is sodium dodecanoate, CnH23C02Na. It belongs to the class of sodium alkylcarboxylates, also called fatty acids or soaps. Just as with SDS in water at neutral pH, the alkali metal dissociates as a cation so that the surfactant becomes... 

The immobilisation of unsaturated surfactant sodium 10-undecenoate [Cl 1( )] and the saturated surfactant sodium dodecanoate (C12) was carried out on PE surfaces [266] by means of an argon plasma treatment and characterised using XPS and SSIMS techniques. The typical SSIMS spectra for unmodified and modified PE films are shown in Fig. 21. The differences in the SSIMS spectra of PE and that of PE/C11( ) and PE/C11( )-Ar 5 are merely the spectra of the surfactant which can be attributed to the presence of a layer of Cll( ) on the PE sample. The SSIMS analysis showed that during... 

Fig. 2.6. Variation of CMC with pressure for sodium dodecanoate (From Ref. 32))...

Fig. 2.19 A-D. Solubility of decanol in solutions of (A) sodium octanoate (20 °C), (B) sodium deca-noate (40 °C), (C) sodium dodecanoate (40 °C) and (D) sodium tetradecanoate (40 °C). Curves a refer to right hand ordinate axes and curves b to left hand ordinate axes. (From Ref.86))...

Figure 10. Adsorption isotherms for surfactants on a PTFE latex at 25°C (-%-) ammonium perfluoro-octanoate at pH 6.0 in 10 3 mol dm"3 ammonium nitrate (-O-) sodium dodecanoate at pH 9.0 in 10 3 mol dm"3 sodium nitrate.

The effect of micellar solutions of sodium dodecanoate (laurate) and n-dodecyltrimethylammonium bromide on the rate of alkaline hydrolysis of p-nitrophenyl acetate, mono-p-nitrophenyl dodecanedioate, and p-nitrophenyl octanoate has been investigated by Menger and Portnoy... 

Fig. 6. Plots of for the hydrolysis of p-nitrophenyl acetate (A), mono-p-nltrophenyl dodecanedioate (B), and p-nitrophenyl ootanoate (C) at pH 9-59, I = 0-1 and 50° vs. sodium dodecanoate (laurate) concentration (on the left) and at pH 10-49, I = 0-2 and 50° vs. n-dodecyltrimethylammonium bromide (LTAB) concentration (on the right). Values of k,/, for the reaction of A -with sodium laurate have been divided by 2-0 to bring the curve on scale (Menger and Portnoy, 1967).

The presence of medium chain fatty acids and glycerides in food products has stimulated interest in their potential utility as absorption enhancers. Some fatty acids and glycerides have been shown to increase drug absorption under a variety of conditions, almost always in animals and in most cases after rectal dosing. However, some studies have yielded positive results after oral dosing. Oral insulin bioavailability was increased to 9-13% relative to IM administration by a mixture of sodium dodecanoate and cetyl alcohol. Aftiraxone absorption was enhanced by glyceryl-1-monooctanoate after oral, duodenal, and rectal administration to animals. 

Hydrolysis of 2-t-butyl-3-phenyloxaziridine is enhanced by a factor of 68 on addition of sodium dodecanoate, by a micellar effect. ... 

Potassium laurate (potassium dodecanoate) [10124-65-9] M 338.4. Recrystallise it three times from EtOH [Neto Helene J Phys Chem 91 1466 1987]. [Beilstein 2 H 360,2 I 156,2 II 318, 2 HI 880, 2 IV 186.] See purification of sodium dodecanoate below. 

Sodium dodecyl sulfate Sodium dodecanoate (laurate) Hexa-ethylene glycol monododecyl ether 1 -octadecanoy 1-sn-glycerol (monostearin) Hexadecyltrimethyl ammonium chloride Dioctadecyldimethyl ammonium chloride... 

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