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Small interfering ribonucleic acid siRNA

Transferrin-containing CD polymer-based nanoparticles were studied as nucleic acid delivery system that can be modified for targeted delivery of small interfering ribonucleic acid (siRNA) to cancer cells. Molecular studies showed that the siRNA CD nanoparticles reduced levels of Ewing s transcript by 80% and inhibited growth of cultured Ewing s tumor cell line. It was also reported that this delivery system indicated a lack of toxicity [39],... [Pg.1232]

This chapter briefly describes the synthesis of a variety of cationic polymers by LRP and their applications as deojqnribonucleic acid (DNA) and small interfering ribonucleic acid (siRNA) delivery agents. The polymers of different shapes, architectures and molecular weights will be compared for their gene expression profiles. Moreover, the S3mthesis of polymeric... [Pg.64]

See other pages where Small interfering ribonucleic acid siRNA is mentioned: [Pg.541]    [Pg.780]    [Pg.1271]    [Pg.1338]    [Pg.22]    [Pg.50]    [Pg.78]    [Pg.57]    [Pg.541]    [Pg.780]    [Pg.1271]    [Pg.1338]    [Pg.22]    [Pg.50]    [Pg.78]    [Pg.57]    [Pg.597]    [Pg.112]    [Pg.312]    [Pg.98]    [Pg.181]    [Pg.440]    [Pg.628]    [Pg.212]    [Pg.728]    [Pg.5]   


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Interfering

Ribonucleic acid small

SiRNA

SiRNAs

Small interfering ribonucleic acid

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