Skin irritation nitrates organic

Organic heat-transfer fluids require stringent leakage control because they are all flammable from 180 to 540 °C (356 to 1000 °F) [10], and most of the fluids irritate eyes and skin [9]. Although a nitrate salt mixture is nonflammable, it is a strong oxidizing agent and thus should not contact flammable materials. 

DOT CLASSIFICATION 5.1 Label Oxidizer SAFETY PROFILE Moderately toxic by intraperitoneal route. Severe skin and eye irritant. A powerful oxidizer which has caused many explosions in industry. Potentially explosive reactions with alkenes (above 220°C), ammonia, arjl hydrazine + ether, dimethyl sulfoxide + heat, ethylene oxide, fluorobutane + water, organic materials, phosphorus, trimethyl phosphate. Reacts to form explosive products with ethanol (forms ethyl perchlorate), cellulose + dinitrogen tetraoxide + oxygen (forms cellulose nitrate). Avoid contact with mineral acids, butyl fluorides, hydrocarbons. A drying agent. When heated to decomposition it emits toxic fumes of MgO and Cr. See also MAGNESIUM COMPOUNDS and PERCHLORATES. 

Collodions are preparations of cellulose nitrate (pyroxylin) dissolved in an organic solvent. The solvent evaporates rapidly and the resultant flexible film is used to hold a medicament, e.g. salicylic add, in contact with the skin. They are irritant and inflammable and are used to treat only small areas of skin. 

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