Single-molecule dynamics

Xie X S and Dunn R C 1994 Probing single molecule dynamics Science 265 361-4... 

Yang H, Xie XS (2002) Statistical approaches for probing single-molecule dynamics photon-by-photon. Chem Phys 284(1-2) 423 t37... 

In AFM single molecule dynamic force spectroscopy (AFM-FS), binding forces between two molecules of interest are measured by functionally immobilizing them on two different surfaces (i.e. the tip of an AFM and an appropriate counter surface) that are brought in mechanical contact under physiological conditions (see Figure 2). 

Woicik, M., and Clementi, E., Single molecule dynamics of three body water, J. Chem. Phys. 85, 3544-3549 (1986). 

Edel, J. B., Wu, M., Baird, B., and Craighead, H. G. (2005). High spatial resolution observation of single molecule dynamics in living cell membranes. Biophys. J. 88 L43-L45. 

T. Yanagida, Y. Ishii, Single Molecule Dynamics in Life Science (Wiley-VCH, 2008)... 

Mayne, A.J., Dujardin, G., Comtet, G. and Riedel, D. (2006) Electronic control of single-molecule dynamics. Chem. Rev.,... 

High-resolution in situ STM as well as phase transition dynamics of nucleobases on Au(lll) and other low-index electrode surfaces supported by infrared spectroscopy have been reviewed recently by Nichols and coworkers [142] and Wandlowski and coworkers [143]. We refer to these reviews for details and note instead another aspect of single-molecule dynamics of DNA-based molecules. The observed electronic conductivity of oligonucleotides of variable length and variable base composition has opened almost a Pandora s box of novel DNA-based electronic properties. These include particularly photochemical and interfacial electrochemical ET. We refer to other recent reviews [144, 145] for this, still far from settled, issue but note the following STM-based studies that illuminate the conductivity issue at the single-molecule level (Figure 2.4). 

Betzig E and Trautman J K 1992 Near field optics microscopy, spectroscopy, and surface modification beyond the diffraction limit Science 257 189-95 Xie X S and Dunn R C 1994 Probing single molecule dynamics Science 265 361-4 Ambrose W P, Goodwin P M, Martin J C and Keller R A 1994 Alterations of single molecule fluorescence lifetimes in near-field optical microscopy Science 265 364-7... 

Ha T, Enderle T, Chemla D S, Selvin P R and Weiss S 1996 Single molecule dynamics studied by polarization modulation Phys. Rev. Lett. 77 3979-82... 

Ha, T, Enderle, T, Chemla, DS, Selvin, PR, and Weiss, S, Single molecule dynamics studied by polarization modulation.P/iysicn/Revien Ietrers77(1996) 3979-3982. 

M. Wojcik and E. dementi,/. Chem. Phys., 85, 3544 (1986). Single Molecule Dynamics of Three-Body Water. 

Yang, H. and Xie, X.S., Probing single molecule dynamics photon by photon,/. Chem. Phys., 117, 10965, 2002. 

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