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Single chain Fv fragments

Fischer, R., Schumann, D., Zinunermann, S., Drossard, J., Sack, M., and Schillberg, S. (1999). Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants. Ear. J. Biochem. 262 810-816. [Pg.51]

Single-chain Fv fragments (scFv) consisting of VH and VL regions linked by a flexible peptide... [Pg.449]

Several systems exist for the expression and cloning of antibodies, as either Fab fragments (Fabs) or single-chain Fv fragments (scFvs) on the surface of... [Pg.461]

Kipryanov, S. M, Little, M, Kropshofer, H., Breitling, F., Gotter, S., and Diibel, S. (1996) Affinity enhancement of a recombinant antibody, formation of complexes with multiple valency by a single-chain Fv fragment-core Streptavidin fusion. Protein Eng 9,203—211... [Pg.499]

Biocca, S., Ruberti, F., Tafani, M., Pierandrei-Amaldi, P., and Cattaneo, A. (1995) Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria. Biol Technology 13, 1110-1115. [Pg.211]

Fig. 3.4 Modes of action of monoclonal antibodies in cancer therapy. scFv single-chain Fv fragment. (Reproduced from Carter, P. 2001. Improving the efficacy of antibody-based cancer therapies. Nat. Rev. Cancer1 118-129). Fig. 3.4 Modes of action of monoclonal antibodies in cancer therapy. scFv single-chain Fv fragment. (Reproduced from Carter, P. 2001. Improving the efficacy of antibody-based cancer therapies. Nat. Rev. Cancer1 118-129).
Kubetzko S, Balic E, Waibel R, Zangemeister-Wittke U, Pluckthun A. PEGylation and multimerization of the anti-pl85HER-2 single chain Fv fragment 4D5 effects on tumor targeting. J Biol Chern 2006 281 35186-201. [Pg.665]

Leclerc E, Liemann S, Wildegger G, Vetter SW, Nilsson F (2000) Selection and characterization of single chain Fv fragments against murine recombinant prion protein from a synthetic human antibody phage display library. Hum Antibodies 9 207-214. [Pg.722]

Worn, A. Pltickthun, A., Stability engineering of antibody single-chain fv fragments,./. Mol. Biol. 2001, 305, 989-1010... [Pg.247]

Kortt, A. A., Lah, M., Oddie, G. W., Gruen, L. C., Bums, J. E., Pearce, L. A., et al. (1997) Single chain Fv fragments of anti-neurominidase antibody NC10 containing five and ten residue link-... [Pg.90]

In future, many antibody-derived molecules will be seen in many indications, in addition to single chain Fv fragments (scFv). Dimeric and tetrameric mini-antibodies, diabodies, single antibody domains, Fv fragments fused to toxins, cytokines, antibiotics or radionuclides, protein scaffolds with hypervariable antibody domains, and related molecules such as an-ticalines will emerge to complement the toolbox of affinity-based agents and enhance their therapeutic efficacy. [Pg.1137]

Eldin, P., Pauza, M.E., Hieda, Y, Lin, G., Murtauch, M.P., Pentel, P.R., Pennell, C.A., High level secretion of two antibody single chain Fv fragments by Pichia pastoris. J. Immunol. Methods 1997, 201, 67-75. [Pg.1144]

Single-chain Fv fragments Accumulation and storage of Potato Phytochrome binding AMT 11,21... [Pg.205]


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See also in sourсe #XX -- [ Pg.210 ]




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