Single-cell recording

Ludvig N, Potter PE, Fox SE. 1994. Simultaneous single-cell recording and microdialysis within the same brain site in freely behaving rats a novel neurobiological method. J Neurosci Methods 55(1) 31-40. 

The long-held dichotomy of macrosmatic and microsmatic vertebrates is no longer tenable. Neuroanatomists had assumed that taxa with relatively few olfactory receptor cells and small olfactory bulbs would also be inferior in olfactoiy performance (threshold and number of compounds detected) to those with more receptors and larger bulbs. However, we now know from single-cell recordings that a particular receptor cell type can respond to a wide range of odor compounds that share certain features. Keverne (1983) pointed out that the olfactory bulbs act as a filter, while more complex pattern analysis takes place in the neocortex. The more evolved the neocortex, as in primates, the... 

The inferior longitudinal fasciculus follows the ventral stream and involves a pathway conjoining the primary visual cortex with the inferior temporal cortex. It is believed to be involved in object identification by integrating feature analysis with object discrimination. Single cell recordings from area V4 of the extrastriate cortex during covert orientation of attention reveal an in-... 

Bogner, F. and Boppre, M. (1989). Single cell recordings reveal hydroxydanaidal as the volatile compound attracting insect to pyrrolizidine alkaloids. Entomologia Experimentalis et Applicata 50 171-184. 

Sakmann B, Neher E (1995) Single-cell Recording. Plenum Press, New York... 

Recently electrophysiological experiments by Sasz have yielded results which would indicate that not only periplanone-B, but also periplanone-A could be a genuine pheromone. With single cell recording techniques he demonstrated the presence of many olfactory hairs on the antennae of Periplaneta americana that were very sensitive to periplanone-A, whereas others were sensitive for periplanone-B (41). 

WADHAMS, L. J., Coupled gas chromatography - Single cell recording a new Technique for use in the analysis of insect pheromones, Z. Naturforsch., 1982, 37c, 947-952. 

A further extension of GC-EAD is the use of single cell recording when the response of an individual olfactory cell is monitored. The basic set-up is the... 

Aghajanian, G. K., and Bunney, B. S., 1977, Dopamine Autoreceptors pharmacological characterization by microiontophoretic single cell recording studies, Naunyn-Schmie-deberg s ArcA. Pharmacol. 297 1-7. 

In the brain, synchronization and oscillation cause and affect each other. Synchronization can occur as a result of the neuronal oscillations, in which case the synchronization is called oscillation-based synchronization. On the other hand, oscillations can occur as a result of synchronization. This happens, for instance, when the occurrence of firing in a neuron predicts the occurrence of firing in the next neuron with some probability. Thus, neuronal oscillations in the brain are related to synchronization. Since oscillations and synchronization in the brain involves more than one neuron, there is no possibility that one can infer whether a single neuron is in synchrony with the others by making single cell recordings. We absolutely need to measure collective field potentials [14,15]. 

Aghajanian GK, Bunney BS (1977) Pharmacological characterization of dopamine autoreceptors by microiontophoretic single-cell recording studies. Adv Biochem Psychopharmacol 16 433-438... 

ERGs, the measurement of whole-retina extracellular electrical response to light stimuli. The on- and off-ERG transients provide a crude massed measurement of synaptic activity downstream from photoreceptor activation. Records can also be made with intracellular electrodes of single photoreceptor responses in the intact eye. More recently, research has focused on single-cell recordings from isolated or semi-isolated photoreceptors in vitro. 

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