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Simulated biological fluid, solubility

One of the major factors influencing biological availability and toxic action of particle-bound metal compounds is their solubility under the pH and ionic strength conditions of human body fluids. Mullins and Norman (1994) measured metals in windblown dust from mine wastes as a function of particle size, which determines where in the respiratory tract the particle-bound metals will eventually settle, and as a function of solubility in different body fluids. They found that compounds of Cd and Mn in the < 10-pm fraction were highly soluble in simulated stomach fluid (40 to 91%) and simulated lung fluid (27 to 100%). Compounds of As were fairly soluble in stomach fluid (17 to 37%) but not in lung fluid (0.1 to... [Pg.230]

See other pages where Simulated biological fluid, solubility is mentioned: [Pg.89]    [Pg.89]    [Pg.89]    [Pg.90]    [Pg.122]    [Pg.60]    [Pg.4784]    [Pg.106]    [Pg.243]    [Pg.489]    [Pg.36]    [Pg.983]    [Pg.84]    [Pg.196]   
See also in sourсe #XX -- [ Pg.89 ]



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