Silk fibroin sponge

Wongpanit, P., SanchavanaMt, N., Pavasant, P., Bunapraseit, T., Tabata, Y., Rujiravanit, R. Characterization of Chitin Whisker-ReinfOTced Silk Fibroin Nanocomposite Sponges Eur. Polym. J. 43, 4123-4135 (2007)... 

Gotoh, Y., Ishizuka, Y., Matsuura, T., Niimi, S., 2011. Spheroid formation and expression of liver-specific functions of human hepatocellular carcinoma-derived FLC-4 cells cultured in lactose-silk fibroin conjugate sponges. Biomacromolecules 12, 1532—1539. 

Roh, D., Kang, S., Kim, J., Kwon, Y., Young Kweon, H., Lee, K., Park, Y, Baek, R., Heo, C., and Choe, J. (2006). Wound healing effect of silk fibroin/alginate-blended sponge in full thickness skin defect of rat. Journal of Material Science Material in Medicine 17, 547-552. 

Xiaomeng, L., Li, B., Ma, J., Wang, X., Zhang, S. (2014). Development of a silk fibroin/ HTCC/PVA sponge for chronic wound dressing. Journal of Bioactive Compatible Polymer, 29, 398—411. 

One of the most difficult challenges in tissue engineering is the vascularization of engineered constructs. A recent paper described the development of a scaffold that incorporated silk fibroin fibers into a salt-leached sponge made of poly(D,L-lactic acid) (PDLLA) (Stoppato et al., 2013). The addition of silk fibroin fibers to the PDLLA salt-leached sponge increased the scaffold stiffness and heightened its capacity to support endothelial cells in vitro, and the in vivo perfusion revealed a faster vascularization of the composite scaffolds. 

Albuininnicls Insoluble in ull solvents In keratm of hair, nails, and fenllters collagen of connective tissue ehnndrin of cunilnge fibroin of silk and spongin of sponges... 

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