Signal transduction I

Activation of cAMP-dependent protein kinase and subsequent protein phosphorylation 

Activated (phosphorylated) protein or transcription factor (see Section 1.5) 

Catalytic domain Phosphate residue Regulatory domain 

ADP Adenosine diphosphate ATP Adenosine triphosphate cAMP Cyclic adenosine monophosphate 

DNA Deoxyribonucleic acid mRNA Messenger ribonucleic acid 

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Arachidonic acid—Metabolism. 2. Arachidonic acid—Physiological effect. 3. Cellular signal transduction. I. Title. II. Series. 

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Bissantz C. Conformational changes of G protein-coupled receptors during their activation by agonist binding. I Recept Signal Transduct Res 2003 23(2-3) 123-153. 

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The revisions in the second edition include two new chapters, Membranes and Membrane Proteins and Signal Transduction Pathways. These topics are related to the explosion of new information about cell signaling and signal transduction pathways. In addition, I ve added some tables of information that I think will be helpful in seeing the big picture (and remembering some of the more important details). As before, the major topics and things to remember are set off in boxes so that if you already know everything in the box, you can skip the rest of the section. 

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