Shelves storage

The final test of stability is, of course, obtained by shelf storage data, by placing the material under the conditions that will be encountered in commercial practice. But there are many problems encountered in the determination of shelf storage stability. 

A sealed ampoule burst after shelf storage for several months. Store only under refrigeration. 

Vacuum distilled material kept dark for 6 months was found to have largely polymerised to a yellow solid, which exploded 15 days later [1], A bottle of uninhibited distilled material exploded after shelf storage for several months [2], It may be stored for several months out of contact with air under refrigeration. In contact with ambient air, it polymerises slowly, but rapidly in contact with acidic materials [3], See Other CYANO COMPOUNDS, POLYMERISATION INCIDENTS... 

A brown glass bottle containing 700 g of the salt exploded forcefully after shelf storage for 2 weeks. 

When experience or shelf-storage experiments indicate that a preservative is required in a pharmaceutical preparation, its selection is based on many cross considerations including some of the following ... 

A glass container exploded after shelf storage for several months, (probably from internal gas pressure arising from slow hydrolysis by atmospheric or adsorbed moisture). See other GAS EVOLUTION INCIDENTS... 

Long shelf storage without damage to any part of the tourniquet... 

The polymer carrier should remain stable and durable during coating, crimping, sterilization, packaging, shelf-storage, and implantation, Physical stability of the polymer is necessary to... 

PET bottle Aseptic filling and shelf storage 10 days at 40 °C... 

Figure 6.21 Shelf storage of pesticides. Packages labeled and labels visible. 

Shelf Storage Test The test material is stored under similar conditions as in retail and is evaluated for the effectiveness of antioxidants in prolonging the premium quality of the product. Periodic evaluation of the hpid oxidation products (primary or secondary) by chemical tests (e.g., peroxide value, conjugated diene value, 2-thiobarbituric acid reactive substances, hexanal content) or sensory evaluation will be used to find out the onset of oxidation. The main drawback of this kind of evaluation is the time taken therefore, rapid evaluation or accelerated methods are often preferred (19, 51). 

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