Services assay kits

Caliper Life Sciences also provides a CE based kinase panel. The Caliper Life Sciences panel consists of 177 wt kinases (including some lipid kinases) and 12 mutant kinases. This company provides kinases and substrates on assay plates and is not strictly a screening service, but it could be a good way forward for labs that have access to a Caliper CE instrument. The company does also provide a smaller panel as a screening service. For more information about both of these, see http //www.caliperls.com/products/reagents/kinase-profiling/ profilerpro-kinase-selectivity-assay-kits.htm. 

It is essential that test-kits are used for the intended purpose in a specific matrix. Thus test-kits can limit the applications in which the technology can be applied. In some cases, it will be necessary to set up an in-house assay format for which it will be necessary to buy the separate individual immunoreagents, such as antibodies, enzyme-tracer or analyte-derivative protein conjugates. In some cases this is difficult because the quality and supply are not always guaranteed. A recent list of antibody manufacturers, suppliers and services is given by Blow, 2007. 

Products/technologies Unique gene response profiles provide mechanistic information that can be used to optimize drug leads, as well as automated assays for screening drug leads for safety. Tools are offered as kits for customers to perform in their own laboratories or as a service through Xenometrix s Customer Research Laboratory. 

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