Serum response factor

Steroid and thyroid hormone receptors NFkB-IKB family Serum response factors... 

Chemoenzymatic Synthesis of a Characteristic Glyco-phosphopeptide from the Transactivation Domain of the Serum Response Factor, J. Sander H. Waldmann, Angew. Chem 1999, 111, 1337-1339, Angew. Chem Int. Ed. 1999,38,1250-1252... 

Spencer, J.A., Baron, M.H., and Olson, E.N. (1999) Cooperative transcriptional activation by serum response factor and the high mobility group protein SSRPl. J. Biol. Chem. 274, 15686-15693. 

Gruenberg, D. A., S. Natesan, C. Alexandre, M. Z. Gilman. Human and Drosophila homeo domain proteins that enhance the DNA-binding activity of serum response factor. Science 257 1089-1095, 1992. 

Mao, J., Yuan, H., Xie, W., and Wu, D. (1998). Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit G alphal3. Proc. Natl. Acad. Sci. USA 95, 12973-12976. 

Park, B., Nguyen, N. T., Dutt, P., Merdek, K. D., Bashar, M., Sterpetti, P., Tosolini, A., Testa, J. R., and Toksoz, D. (2002). Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNALl, supports serum response factor activation. /. Biol. Chem. 277, 45361-45370. 

Browning, C.L., Culberson, D.E., Aragon, I.V., Fillmore, R.A., Croissant, J.D., Schwartz, R.J. et al. (1998) The developmental regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes. Dev. Biol., 194, 18-37. 

Carson, J.A., Fillmore, R.A., Schwartz, R.J. and Zimmer, W.E. (2000) The smooth muscle gamma-actin gene promoter is a molecular target for the mouse bagpipe homologue, mNkx3-l, and serum response factor. J. Biol. Chem., 275, 39061-39072. 

Dash, P. K., Orsi, S. A., and Moore, A. N. (2005). Sequestration of serum response factor in the hippocampus impairs long-term spatial memory. J. JVeurochem. 93, 269-278. 

Finally, a synthesis of a glycophosphopeptide sequence 25,5 from the human serum response factor depicts the use of enzyme-labile choline esters and... 

Sotiropoulos, A., Gineitis, D, Copeland, J., and Treisman, R. 1999. Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell 98, 159-169. 

CaMKIV is responsible for calcium-dependent gene transcription through the phosphorylation of transcription factors cAMP response element-binding protein (CREB), serum response factor (SRF), and myocyte enhancer factor-2 (MEF2). Oncoprotein 18 in the cytoplasm is also a substrate of CaMKIV. The activity of CaMKIV is activated by CaMKK and autophosphorylation. The elongation factor-2 is the only known substrate of CaMKIII (eEF-2K) at present. The phosphorylation of elongation factor-2 inhibits its functions. 

SRF serum-response factor TRAIL TNF-related apoptosis inducing ligand... 

Glycosylated amino acids 89 and 90 have been used in solid-phase synthesis of peptide fragments derived from serum response factor and RNA polymerase II [107,108]. 

Lee SK, Na SY, Jung SY, Choi JE, Jhun BH, et al. 2001. Activating protein-1, nuclear factor-kappa B and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2. Mol. Endocrinol. 14 915-25... 

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