Sertindole

C,4Hi C1FN02) see Sertindole [[(3-chloro-4-fluorophenyl)amino]methylene]propane-dioic acid diethyl ester... [Pg.2329]

CjnHjzFNOj 110429-36-2) see Paroxetine 1 -(4-fluorophenyl)-S-chloro- Iff-indole (C14H9CIFN 138900-22-8) see Sertindole... [Pg.2387]

A search of Medline, EMBASE and PsycLIT was conducted in August 2000, using the following terms Amisulpride, clozapine, olanzapine, risperidone, sertindole, zotepine, ziprasidone, economics, healthcare, costs. All manufacturers of atypical antipsychotic drugs were contacted in April 2000 and asked to supply primary reference data on their product, and all companies had complied with this request by August 2000. A further manual search was conducted of files and journals kept in the National Centre for Information on Psychotropics at the Maudsley Hospital. Reference sections from all retrieved papers were scrutinized for further relevant references. [Pg.38]

Sertindole (Serdolect) Schizophrenia Cardiovascular (QT-interval prolongation, potentially fatal arrhythmias) 2000 [57]... [Pg.13]

Dubitsky, G.M. (2000) Clinically important QT interval prolongation with three antipsychotics thioridazine, pimozide, sertindole, FDA. [Pg.20]

Balls, T., Andersen, K., Soby, K.K., and Liljefors, T. al Adrenoceptor subtype selectivity 3D-QSAR models for a new class of al adrenoceptor antagonists derived from the novel antipsychotic sertindole./. Mol. Graph. Mod. 2003, 21, 523-534. [Pg.373]

Examples of recent work carried out by the DSRU includes the examination of mortality rates and cardiac arrhythmias between sertindole and two other at)q)ical antipsychotics, olanzapine and risperidone. Tolterodine, an agent often used for urinary frequency and bladder instability, is the latest drug to be examined by the DSRU.135... [Pg.433]

Wilton LV, Heeley El, Pickering RM, et al. Comparative study of mortahty rates and cardiac dysrhythmias in post-marketing surveillance studies of sertindole and two other atypical antipsychotic drugs, risperidone and olanzapine. J Psychophar-macol 2001 15 120-6. [Pg.451]

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