Serlect - Sertindole

Clozapine (Clozaril ) 8, Zotepine (Zoleptil ) 9, Sertindole (Serlect )... 

Atypical or nontraditional antipsychotic medications have fewer movement symptoms than the typical antipsychotics. Examples of these medications include (see Table 7.3) clozapine (Clozaril), risperidone (Risperdal), sertindole (Serlect), olanzapine (Zyprexa) and quentiapine (Seroquel). These medications have gained popularity because they appear to have lower EPS proflles and they help individuals to think more clearly and follow directions better, to learn new facts and master new skills, and to interpret emotion more accurately (Lambert, 1998). 

Drug interactions with this new classification of atypical medications are multiple. Therefore, it is essential to take a thorough medication history. Clozapine (Clozaril), risperidone (Risperdal), sertindole (Serlect), olanzapine (Zyprexa), and quentiapine (Seroquel) are fairly new and a long history of use in the practice setting has not been established. There are many side effects and possible interactions that have not been discovered yet. It is imperative that potential drug interactions be recorded and monitored closely for changes in efficacy, toxicity, and if applicable, drug concentration (Lam, 2000). 

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