Sequential screening reactor

Reactor 24 [R 24] High-throughput Gas/Liquid and Liquid/Liquid Dynamic Sequential Screening Reactor... 

Figure 4.64 Schematicofa mixer-tube reactor set-up used forhigh-throughput sequential screening of (i) catalysts and (N) substrates. The substrate (S) is thus treated to form the product (P) [110. ...

Dynamic Sequential Screening in Liquid/Liquid and Gas/Liquid Reactors... 

Screening in stationary mode will only give information about the activity of a single catalyst or a catalyst mixture. When a proper catalyst for a certain reaction is found, the next important information is the reaction kinetics. To obtain this information, several methods and reactors are recommended in the literature [66-73]. Most of them apply transient reactor operations to find detailed kinetic information. Microreactors are particularly suited for such an operation since their low internal reaction volumes enable a fast response to process parameter changes, e.g., concentration or temperature changes. This feature was already applied by some authors to increase the product yield in microreactors [70, 74, 75]. De Belle-fon [76] reported a dynamic sequential method to screen liquid-liquid and liquid-... 

The same groups also reported on a 64-fold ceramic block reactor and a ceramic monolithic reactor for the screening of up to 250 catalysts in parallel (Figure 3.41). The catalyst array was prepared via an incipient wetness method by combination of different amounts of Pt, Zr and V on the alumina walls of the monolith by means of an automatic liquid handler. Gas samples from each channel of the monolith were analyzed sequentially by a quadrupole mass spectrometer by moving a capillary sampling line into the channels with the help of a three-dimensional positioning system [69],... 

Most gas-phase reactions of interest, however, have a complex product distribution, can be sequential, and are to some extent catalyzed by many different catalysts examples are the partial oxidation reactions. For this class of reactions, a parallel testing would be much better than cocktail screening, as in this case promising catalysts could be directly identified. The drawback of parallel screening, however, is the more complex reactor design and the fact that a parallel analysis or, at least, a relatively fast sequential analysis is necessary. 

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