Separator Acclaim Mixed-Mode silica columns

Acclaim HILIC-10 is similar to Acclaim Mixed-Mode WAX-1. This relatively new column is also based on high-purity spherical silica covalently modified with a proprietary hydrophilic layer. It is suited for use in a broad range of applications including the separation of hydrophilic drugs and their metabolites. Acclaim Mixed-Mode HILIC-1 is a stationary phase that combines both RP and HILIC properties. Unlike traditional RP or HILIC columns, this packing material features a long alkyl chain with a diol functionality at the terminal end. 

The cationic melamine can be separated on Acclaim Mixed-Mode WCX-1 (see Section 6.7.2) using an ammonium acetate buffer as the eluent. This column features a mixed-mode silica-based packing material that incorporates... 

Figure 10.201 Gradient elution of anionic surfactants in a shampoo using mixed-mode liquid chromatography on a silica-based column. Separator column Acclaim Surfactant Plus,...

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