Separation mass spectrometry

Gelpi, E. (2002). Interfaces for coupled liquid-phase separation/mass spectrometry techniques. An update on recent developments.. Mass Spectrom. 37, 241—253. 

Trim P, Henson C, Avery J, McEwen A, Snel M, Claude E, Marshall P, West A, Princivalle A, Clench M (2008) Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections. Anal Chem 80 8628-8634. doi 10.1021/ac8015467... 

This section is concerned with just one aspect of the relatively new development that has been termed in various ways such as mass separation/mass spectrometry or mass spectrometry/mass spectrometry (both offering the same acronyms MS/MS), two-dimensional mass spectrometry, tandem mass spectrometry, etc.. The acronym MS/MS is the most appropriate and is certainly the most widely used. The definitions and the nomenclature relevant to these techniques will be introduced as they will arise in our mathematical development of the scan laws. 

Introducing Proteomics From Concepts to Sample Separation, Mass Spectrometry and Data Analysis. 2011. 

Mayne, L., Kan, Z.Y., Chetty, P.S., etal. (2011) Many overlapping peptides for protein hydrogen exchange experiments by the fragment separation-mass spectrometry method. J Am Soc Mass Spectrom, 22 (11), 1898-1905. 

L. Mayne, Z.-Y. Kan, P. S. Chetty, A. Ricciuti, B. T. Walters tmd S. W. Englander. (2011) Many Overlapping Peptides for Protein Hydrogen Exchtmge Experiments by the Fragment Separation-Mass Spectrometry Method, Journal of the American Society for Mass Spectrometry, 22, 1898-1905. 

See also Drug Metabolism Metabolite Isolation and Identification. Liquid Chromatography Isotope Separations. Mass Spectrometry Stable Isotope Ratio. 

Lovric, J. Introducing Proteomics, from Concepts to Sample Separation, Mass Spectrometry and Data Analysis. Wiley-Blackwell Oxford, U.K., 2011. 

Smith, R.D., Shen, Y. and Tang, K., Ultrasensitive and quantitative analyses from combined separations-mass spectrometry for the characterization of proteomes. Acc. Chem. Res., 37, 269-278 (2004). 

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