Scopolamine methylbromide

Synonyms. Epoxymethamine Bromide Hyoscine Methylbrom-ide Methoscopolamine Bromide Scopolamine Methylbromide. Proprietary Names. Holopon Pamine. 

Schiff s bases in gas chromatography, 188 Schiff s Reagent, 144 Schoenocuulon officinale, 1061 Scolaban, 409 Scoline, 998 Scoparium, 972 Scopolamine, 674 Scopolamine bromhydrate, 674 Scopolamine butylbromide, 675 Scopolamine hydrobromide, 674 Scopolamine methylbromide, 675... 

Synonyms 7-(3-Hydro y-l oxo-2-phenylpropo y)-9,9-dimethyl 3-oxa-9-azoniatricyclo[3.3.1.O lnonane bromide scopolamine methylbromide Trade names Famine... 

Methscopolamine Methscopolamine, 7-(3-hydroxy-l-oxo-2-phenylpropoxy)-9, 9-dimethyl-3-oxa-9-azoniticyclo[3.2.1.0. " ]nonane nitrate (14.1.7), is synthesized by reacting scopolamine (14.1.6) with methylbromide and sometimes with a subsequent replacement of the bromide ion with a nitrate ion by using silver nitrate [9,10]. 

Butylscopolamine and methscopolamine bromide, quaternary ammonium derivatives of scopolamine without its central actions and homatropine methylbromide, a quaternary derivative of homatropine, are less potent than atropine in antimus-carinic activity. They are used for their antispasmodic action in gastroenterology. The usual oral doses act for 6-8 hours. However, the quaternary ammonium derivatives are poorly absorbed after an oral dose and their eficacy is therefore very variable. Only parenteral administrations are recommended. 

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