Scale-up of Two-Phase Reactions

1 Scale-up of Gas-Liquid Reactions. The many types of gas-liquid reactions require different considerations on scale-up. In addition to the discussions 

Physical manipulation of such films may be possible through variation in mixing intensity, primarily by local shear. Such interactions would be very scale dependent and could readily be masked in smaller scale operations. The extent to which reactions can be affected by coating of particles is illustrated in an excellent example by Wiederkehr (1988). This study also includes other aspects of reaction system design, such as the choice of continuous smaller volume reactors over batch reactors to reduce the size (and potential energy) of the reacting mass as well as the criticality of residence time distribution in complex reactions. 

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