Scale-up, Flow Distribution and Interface to the Macroscopic World

Scale-up, Flow Distribution and Interface to the Macroscopic World Micro Structured Reactor Scale-up 

Before scale-up in micro structured reactor plants is discussed, a short introduction to problems which occur during scale-up from a miniplant to a production plant will be given. Experimental correlations found in a miniplant will have to be transferred to the geometric scale of a production plant. Some scale-up factors which have been tested successfully for a number of devices are given in Table 4.10 [16, 137-139], 

Tubular bundle reactors, homogeneous tubular reactors, stirred tank reactors 10 000 

It is obvious from Table 4.10 that scale-up is more and more critical if either heterogeneous phase systems or solid phases are incorporated. Scale-up is also strongly influenced by heat and mass transfer if the construction of the devices has a dominant effect on the transfer [137]. 

External numbering-up is numbering-up in the truest sense. Virtually, the complete fluid path is repeated. This resembles also the real meaning of scaling-out. 

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