Scale-Up and Monitoring of the Wet Granulation Process

As the behavior of the wet granulation process cannot be described so far adequately by mathematical equations, the dimensionless groups have to 

According to Buckingham s theorem, the following dimensionless groups can be identified  

Froude number (centrifugal/gravitational energy), geometric number (ratio of characteristic lengths). 

In general, however, it may not be the primary goal to know exactly the empirical parameters a, b, c, d, and e of the process under investigation, but to check or monitor pragmatically the behavior of the dimensionless groups (process variables and dimensionless constant) in the small- and 

In the case of the wet granulation process in a mixer/kneader, the granulation process can be easily monitored by the determination of the power consumption (6-9) (Fig. 1). 

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