SARS-associated coronavirus

H. W. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Lancet 2003, 361, 2045-2046. 

Ko, P. C., Chen, W, Ma, M. H., Chiang, W, Su, C., Huang, C., et al. (2004). Emergency medical services utilization during an outbreak of severe acute respiratory syndrome (SARS) and the incidence of SARS-associated coronavirus infection among emergency medical technicians. Academic Emergency Medicine, 11, 903-911. 

SARS is also a disease in the news over recent years and a plastic resistant to SARS has been mentioned in some journals. From the Centre for Disease Control www.cdc.gov) fact sheet on SARS dated 13 January 2004, SARS is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus. 

Ding Y, He L, Zhang Q, et al. Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-Co-V) in SARS patients Implications for pathogenesis and virus transmission pathways. J Pathol. 2004 203 622-630. 

Sheih WJ, Cheng-Hsiang H, Paddock CD, et al. Immunohis-tochemical, in situ hybridization, and ultrastructural localization of SARS-associated coronavirus in lung of a fatal case of severe acute respiratory syndrome in Taiwan. Hum Pathol. 2005 36 303-309. 

Li S, Chen C, Zhang H, Guo H, Wang H, Wang L, Zhang X, Hua S, Yu J, Xiao P, Li R, Tan X (2005) Identification of natural compounds with antiviral activities against SARS-associated coronavirus. Antiviral Res 67 18... 

Prevalence of IgG antibody to SARS-associated coronavirus in animal traders— Guangdong Province, China, 2003. MMWR Morb Mortal Wkly Rep, 52, 986-987 (2003). 

Sainz B Ir, Mossel EC, Peters CJ, Garry RF (2004) Interferon-beta and interferon-gamma syner-gistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus (SARS-CoV). Virology 329 11-17... 

SARS-CoV Severe Acute Respiratory Syndrome associated coronavirus... 

Severe Acute Respiratory Syndrome associated coronavirus (SARS-CoV) Lycoris radiate, Artemisia annua Showed potent antiviral activities against SARS-CoV in vitro Li et ak (2005a)... 

Helicase has also been a focal point for the development of antiviral chemotherapy of the coronavirus associated with severe acute respiratory syndrome (SARS) in humans. Although several experimental compounds with nucleic acid binding activity showing effective inhibition of SARS-CoV helicase were reported in 2005, there have been no reports of any further development since that time (Kesel 2005). It remains to be seen whether the S ARS-CoV compounds will be developed further, especially since no new infections have been observed in recent years. 

Peiris JS, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, Nicholls J. et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia a prospective study. Lancet 2003 361 1767-72. 

Therefore, in this chapter we will discuss some recent findings on the proteomics of DNA and RNA viral infections that are associated with clinically important diseases in humans, including human cytomegalovirus (HCMV), herpes simplex virus (HSV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), hepatitis B and C (HBV and HCV, respectively), and adenovirus, as well as the coronavirus that causes severe acute respiratory syndrome (SARS). 

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