Salmonella microsome mutagenicity test

McCann, J. Ames, B. "The Salmonella/Microsome Mutagenicity Test Predictive Value for Animal Carcinogenicity " in "Origins of Human Cancer " Hiatt, H. H., Watson, J. D., Winsten, J. A., Eds., Cold Springs Harbor Laboratory Cold Springs Harbor, New York, 1977, pp. 1431-50. [Pg.179]

McCann, J. and Ames, B. N., The Salmonella/Microsome Mutagenicity Test Predictive Value for Animal Carcinogenicity, (p. 1431 in ref. 1)... [Pg.11]

McCann, J., and B.N. Ames. The Salmonella/microsome mutagenicity test predictive value for animal carcinogenicity, pp. 87-108. In W.G. Flaimn and M.A. [Pg.274]

Dose-dependent genotoxic activity of an alcohol extract of frangula was observed in the Salmonella microsome mutagen test and the DNA repair test of primary rat hepatocytes (Helmholz et al. 1993). [Pg.376]

Celanese Chemical Co., Inc., Mutagenicity Evaluation of n-PropylAlcohol in the Ames Salmonella Microsome Plate Test, Litton Bionetics, Inc., Kensington,... [Pg.120]

Ames B.N., McCann J. Yamasaki E. (1975) Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. MutatRes, 31, 347-364. [Pg.490]

Ciba-Geigy Ltd. 1978a. Salmonella/mammalian-microsome mutagenicity test with TK 10 509 (REOFOS 95). Experiment No. 78-2506. Ciba-Geigy Limited, Basle, Switzerland. NTIS OTS0507280. [Pg.336]

Mueller, D., Nelles, J., Deparde, E. and Ami, P. (1980). The activity of S-9 liver fractions from seven species in salmonella/mammalian-microsome mutagenicity tests. Mutat. Res. 70 279-300. [Pg.632]

Ames, B. N., McCann, J. and Yamasaki, E., Methods for Detecting Carcinogens and Mutagens with the Salmonella/Mammalian Microsome Mutagenicity Test , Mutat. Res. (1975) 31, 347. [Pg.11]

Gupta et al. (1987) synthesized the various A-oxidized putative metabolites and esters of ort/20-toluidine and tested them for mutagenic activity in the Salmonella microsome mutagenicity assay. On the basis of these data, they proposed a metabolic... [Pg.301]

Moore, W.B. Chatfield, S.N. (1982) Evaluation of 4-hydroxymethylbiphenyl (4HMB), 4-chloromethylbiphenyl (4CMB) and benzyl chloride (BC) using the Ames Salmonella microsome incorporation test for mutagenicity. Mutat. Res., 100. 35-38... [Pg.475]

Williams, L. R. Preston, J. E. Interim Procedures for Conducting the Salmonella-Microsomal Mutagenicity Assay (Ames Test) Environmental Monitoring Systems Laboratory Las Vegas, NV, 1983 EPA-600/4-82-068. [Pg.47]

Diethylene glycol was not shown to be mutagenic in Salmonella microsome in tests reviewed. Negative results were also obtained in tests for SCE and chromosome aberrations in Chinese hamster ovary cells, reverse mutation tests in Saccharomyces cerevisiae D7, SOS chromotest in Escherichia coli PQ37. Diethylene glycol is not genotoxic. [Pg.849]

Litton Bionetics (1978) Mutagenicity evaluation of TBME-95 in the Ames Salmonella/ microsome plate test. Litton Bionetics, Kensington, Maryland... [Pg.399]

For an overview and procedures for running the Ames test, see Mortelmans, K., Zeiger, E. The Ames Salmonella/microsome mutagenicity assay. Mutat. Res. 2000, 455, 29-60. [Pg.468]

Ferguson, L. R. Baguley, B. C. Verapamil as a comutagen in the Salmonella/mammaiian microsome mutagenicity test. Mutat. Res. Lett. 1988, 209, 57-62. [Pg.119]

The Ames salmonella-microsome test is a principal sensitive mutagen screening test. Compounds are tested on the mutants of Salmonella typhimurium for reversion from a histidine requirement back to prototrophy. A positive result is seen by the growth of revertant bacteria (which do not require an external histidine source). A microsomal activation system should be included in this assay. The use of five different bacterial test strains are generally required. [Pg.192]

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