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Safety considerations general principles

The general principles or considerations for screening in safety assessments are as follows ... [Pg.116]

Apart from separation considerations, Fig. 6.191 shows a very general principle in safety technology the principle of redundancy, in this case the doubling of components relevant to current and voltage limitation (resistors connected in series, Zener diodes in parallel). [Pg.362]

Considerable experience has now been gathered with submission of applications for biopharmaceuticals. Critical review of this experience has been the basis for development of this guidance that is intended to provide general principles for designing scientifically acceptable preclinical safety evaluation programs. [Pg.172]

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