Sabal serrulata

Cantabrana. Spasmolytic activity of a lipidic extract from Sabal serrulata SR074 fruits further study of the mechanisms underlying this activity. Planta Med 1996 62(6) 507-511. 

SR065 Gutierrez, M., M. J. Garcia de Boto, B. SR075 Cantabrana, and A. Hidalgo. Mecha-nisms involved in the spasmolytic ef-feet of extracts from Sabal serrulata fruit on smooth muscle. Gen Pharmacol 1996 27(1) 171-176. 

Niederpriim, H. J., H. U. Schweikert, and K. S. Zanker. Testosterone 5 t-re-ductase inhibition by free fatty acids from Sabal serrulata fruits. Phytomedi-cine 1994 1 127-133. 

Wagner, H., and H. Flachsbarth. A new antiphlogistic principle from Sabal serrulata. 1. Planta Med 1981 41 244-251. 

Lipophilic extract from Sabal serrulata inhibits contractions in smooth muscu- SR094 lar tissue. AktUrol 1996 27 152-158. 

Fitoterapia 1997 68(3) 195-204. Bombardelli, E., and P. Morazzoni. Serenoa repens (Bartram) J.K. Small. Fitoterapia 1997 68(2) 99-133. Salinero, R., A. Miguel, A. Sevilla Toral, et al. Extracts of Sabal serrulata as adrenergic antagonists and inflammation inhibitors. Patent-Eur Pat Appl-527,101 1993 8 pp. 

SR106 Weisser, H., S. Tunn, B. Behnke, and M. Krieg. Effects of the Sabal serrulata extract IDS 89 and its subfractions on Salpha-reductase activity in human benign prostatic hyperplasia. Prostate 1996 28(5) 300-306. 

SR109 Odenthal, K. P. Phytotherapy of benign prostatic hyperplasia (BPH) with Cucurbita, Hypoxis, Pygeum, Urtica and Sabal serrulata (Serenoa repens). Phytother Res 1996 10 S141-S143. 

SRI 10 Duker, E. M., and L. Kopanski. Inhibition of 5-alpha-reductase activity by extracts from Sabal serrulata. Planta Med 1989 55(6) 587. 

SRI 12 von Kloss, P. Steam vaporizable constituents of pressed juice of Sabal serrulata (Roem et. Schult). Arch-neimforsch 1966 16(1) 95-96. 

SRI 29 Breu, W., M. Hagenlocher, K. Redl, G. Tittel, F. Stadler, and H. Wagner. Antiphlogistic activity of an extract from Sabal serrulata fruits prepared by supercritical carbon dioxide/in vitro inhibition of the cyclooxygenase and 5-lipoxygenase metabolism. Arzneim-forsch 1992 42(4) 547-551. 

Finally, initial studies indicate that the following herbals are likely free of serious side effects chamomile, garlic, ginkgo, peppermint, sabal (Sabal serrulata), saw palmetto, and St. John s wort. 

It is not surprising that fatty acids inhibit COX and LOX enzymes due to their structural similarities with arachidonic acid. A supercritical fluid extract from the fruits of Sabal serrulata (also called Serenoa repens Small. Arecaceae) has been utilized for the treatment of benign prostatic hyperplasia (BPH) and non-bacterial prostatitis. The extract was demonstrated as a dual inhibitor of COX and 5-LOX pathways with IC50 at 28.1 pg/ml and 18.0 (ig/ml, respectively. A further evaluation of the supercritical carbon dioxide extract showed the acidic lipophilic fraction, most likely fatty acids, had the same dual inhibitory activities as the parent extract [121]. 

Serenoa repens (Bartram) Small, Sabal serrulata (Michaux) Nichols, Serenoa serrulatum Schultes (5)... 

DeSwaef SI, Kleibohmer W, Vlietinck AJ. Supercritical fluid chromatography of free fatty acids and ethyl esters in ethanolic extracts of sabal serrulata. Phytochem Anal 1996 7 223-227. 

SAW PALMETTO is the fruit of Sabal serrulata (Mich.) Benth et Hook. (syn. Sermon repms (Bart.) Small), family Arecaceae. The fruits contain fatty acids and steroids, particularly 6-sitosterol, and liquid COj hexane extracts of the berries are commercially available. Pharmacological studies have shown inhibition of 5-a-reductase and a reduction in hormone receptors in prostate tissue. Over 18 clinical trials involving nearly... 

Syn Sabal serrulata (Michx.) Nutt, ex Schult. Schult. f. Serenoa serrulata (Michx.) G. Nichols. 

Source Serenoa repens (Bart.) Small, (syn. Sabal serrulata Schultes and Schultes) (Family Palmaceae). 

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