Ergot, rye

In 1964, two new isomers of the known chanoclavine-I (7) were isolated from the water-soluble fraction of Portuguese rye ergot (8). Interpretation of the physical data, essentially of the NMR spectra, permitted the establishment of the stereochemistry of these three isomers. 

A hypothetical sequence, based mainly on the reported isolation of cMvsergyl-L-valine methyl ester from rye ergot (18) was proposed by Agurell (58). According to him, the biogenesis of ergotamine (68) can be represented as follows ... 

The harvesting of the rye (ergot) crop should not be done with a combine, as these machines pass the grains through a sieve. Most of the ergot would then be lost, as it is much larger than the rye kernels. Rather, the rye plants should be cut down using a hand or mechanical... 

Synonyms cas 129-51-1 secale cornutum rye ergot rye scum crude ergot cornocentin ... 

Bernard P, Istin M, Doignon JL, Grognet JM. Contribution of radioinununology to the pharmacokinetic study of derived alkaloid of rye ergot. Med Armees 1986 14(6) 473. ... 

In a reverse procedure, conidial inoculum of rye ergot to was applied to plants in the following subfamilies and genera ... 

Batrakov, S.G. and Tolkachev, O.N. (1997) The structures of triacylglycerols from sclerotia of the rye ergot Claviceps purpurea (FRIES) TUL. Chem. Phys. Lipids, 86,1-12. 

Table 1 Effect of rye ergot on swine reproduction (from Schneider etal, 1986)...

In addition to linear peptides, one can envisage the existence of cyclic peptides in which there is neither an initial nor terminal amino acid and for which the number of peptide bonds equals the number of amino acids. Of course, one can also postulate the existence of partially cyclic peptides, forming sigma-shaped chains (amino acid is internally linked in the peptide. Therefore, it is possible to have partially cyclic peptides possessing either a terminal (6 ° ) or an initial amino acid (h,n9) Certain peptides possess other structures, e.g., bicyclic and polycyclic, owing to the presence of nonpeptide linkages between amino acids, in addition to the characteristic a-peptide bond. Examples of such structures are penicillins, peptides of rye ergot. 

There are now five known peptides extracted from rye ergot, and they are classified into 2 groups (Table XII). They are all heteromeric polycyclic peptides, containing one molecule of lysergic acid (316,317). 

All the peptides of rye ergot are levorotatory (Table XII). On heating of methanol solutions, or by alcoholic sodium hydroxide treatment, the... 

A few disaccharides are found free in the natural state. Lactose is found in the milk of all mammals to the extent of approximately 5%. Sucrose occurs almost universally throughout the plant Idi dom in the juices, seeds, leaves, fruits, flowers, and roots of plants. The industrial sources of sucrose are usually sugar cane and sugar beet. Trehalose(a, ) is contained in large amounts in rye ergot, fungi, young mushrooms, yeast, and the resurrection... 

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