Rutin, extraction from buckwheat

Rutin extraction from buckwheat was optimally performed using between 50% and 60% ethanol with a 3-hr maceration (Kreft et al., 1999). Repeating the extraction two times was sufficient to extract most of the rutin. Lie et al. (2000) demonstrated the optimization of influencing factors such as extraction temperatures, extraction times, and solvent concentrations in a conventional extraction of dry powdered material of Hypericum perforatum. Applied extraction conditions caused variations to favor different components in the mixture. Higher extraction efficiency was achieved with moderately polar solvents to extract flavonoids such as rutin, isoquercitrin, and quercetin. The optimum extraction conditions for dry Hypericum perforatum leaf powder were determined as 44% to 69% ethanol in acetone with a 5.3- to 5.9-hr maceration at 55°C. 

Citrus bioflavonoids, made by extracting the pulp which remains after juicing oranges and lemons, are available in concentrated form. Sometimes, rose hips, obtained from roses, and rutin, obtained from buckwheat leaves, are included with the citrus bioflavonoids. 

Kreft, S., Knapp, M., and Kreft, I. 1999. Extraction of rutin from buckwheat (Fagopyrum esculen-tum Moench) seeds and determination by capil-... 

Matsui T., Kudo A., Tokuda S., Matsumoto K., Hosoyama H. Identification of a new natural vasorelaxatant compound, (-F) -osbeckic acid, from rutin-free tartary buckwheat extract. Journal of Agricultural and Food Chemistry, 58 10876-10879 (2010). 

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