Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Rubidomycin

Antibiotics with antineoplastic activity continue to appear and rubidomycin (daunomycin, daunorubicin) [455] is currently receiving wide study. [Pg.56]

Bernard J, Paul R, Boiron M, Jacquillat C, Maral R (eds) (1969) Rubidomycin, Springer, NewYork, Berlin, Heidelberg... [Pg.330]

Common Name Daunomicina cloridrato Daunomycin hydrochloride Daunorubucin hydrochloride Rubidomycin hydrochloride... [Pg.1197]

J, van Eys, D, Berry, W, Crist, el al. Treatment intensity and outcome for children with acute lymphocytic leukemia of standard risk. Cancer 63 1466 (1989). si. A. Van dec Does, E, R. van Wering, 5. Sudu. et ai. Effectiveness of rubidomycin in induction therapy with vincristine, prednisone, and 1-asparaginase for standard ride childhood acute lymphocytic leukemia results of a Dutch phase HI study (ALL V). [Pg.256]

Synonyms daunomycin DNR rubidomycin Trade names Cerubidine Daunoxome Indications Acute leukemias Category Antibiotic, anthracycline Half-life 14-20 hours... [Pg.163]

Antibiotics with Antineoplastic Activity - A number of tumor -inhibitory antibiotics form stable complexes with DNA thereby interfering with synthesis of RNA. Three of these antibiotics, actinomycin, mithramycin and daunomycin (which is probably identical to rubidomycin) possess... [Pg.167]

Streptomyces coerulerubidos yielded a tetracyclic aminosugar containing an antibiotic named daunorubicin (rubidomycin, Cerubidine ), which exhibited actinomycinlike antitumor activity. Severe cardiotoxicity, however, limited its clinical use, particularly as single agent therapy. [Pg.126]

Daunorubicin (daunomycin, rubidomycin Cerubidine, others) is available for intravenous use. The recommended dosage is 30 to 60 mg/m daily for 3 days. The agent is administered with appropriate care to prevent extravasation, as severe local vesicant action may result. Total doses greater than 1000 mg/m are associated with a high risk of cardiotoxicity. A daunorubicin citrate liposomal product (Daunoxome) is indicated in the treatment of AIDS-related Kaposi s sarcoma. It is given in a dose of 40 mg/m infused over 60 minutes and repeated every 2 weeks. Patients should be advised that the drug may impart a red color to the urine. [Pg.187]

Daunonibicin (daunomycin, rubidomycin, leukae-momycin, rubomycin C). [Pg.175]

Dubost M, Canter P, Mara R, Ninet L, Pinnert S, Pnid homme J, Werner GH. Un novel antibiotique a properties cytostatique- La rubidomycine. CR Acad Sci 1963 257 1813-1815. [Pg.641]

Maral R, Bourar C, Foumel J, Ganter P, de Raiuld Y, Werner GH. Un nouvel antibiotique doue d activite amitumorale La rubidomycine (13.057 R.P). II. Activity antitumorale experimentale. Arzneim FotKh 1967 17 939-948. [Pg.641]

The anthracycline antiobiotic daunomydn (daunorubidn, rubidomycin) has been obtained as a metabolite of Streptomyces peucitius [263] and shown to have structure (LXIIa). Mild acid hydrolysis of the drug has afforded the aglycone daunomycinone (LXIIb) and the amino sugar daunosamine (LXIII), whose constitutions have been established by chemical and physical... [Pg.37]

Adriamycin and Daunorubicin - The structure and absolute stereochemistry of daunorubicin (15a daunomycin, rubidomycin) were determined.98... [Pg.135]

See other pages where Rubidomycin is mentioned: [Pg.430]    [Pg.192]    [Pg.1195]    [Pg.415]    [Pg.1871]    [Pg.1871]    [Pg.91]    [Pg.251]    [Pg.169]    [Pg.238]    [Pg.127]    [Pg.445]    [Pg.430]    [Pg.430]    [Pg.59]    [Pg.580]    [Pg.603]    [Pg.641]    [Pg.158]    [Pg.213]    [Pg.588]    [Pg.484]    [Pg.245]   
See also in sourсe #XX -- [ Pg.158 , Pg.213 ]

See also in sourсe #XX -- [ Pg.37 ]

See also in sourсe #XX -- [ Pg.484 ]



SEARCH



Daunorubicin (daunomycin, rubidomycin

© 2024 chempedia.info