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Daunorubicin citrate liposomal

DAUNORUBICIN CITRATE LIPOSOMAL (DaunoXome solution for injection 2 mg/mL)... [Pg.187]

Daunorubicin (daunomycin, rubidomycin Cerubidine, others) is available for intravenous use. The recommended dosage is 30 to 60 mg/m daily for 3 days. The agent is administered with appropriate care to prevent extravasation, as severe local vesicant action may result. Total doses greater than 1000 mg/m are associated with a high risk of cardiotoxicity. A daunorubicin citrate liposomal product (Daunoxome) is indicated in the treatment of AIDS-related Kaposi s sarcoma. It is given in a dose of 40 mg/m infused over 60 minutes and repeated every 2 weeks. Patients should be advised that the drug may impart a red color to the urine. [Pg.187]

Ambisome , Daunoxome , liposomal amphotericin B and daunorubicin citrate injection. Liposomal lurtotecan in phase I clinical trials. Gilead Sciences Inc., Foster City, CA. [Pg.371]

The citrate salt of daunorubicin is marketed as a liposomal formulation (Fig. 42.17), which promotes the use of this agent in solid tumors. Like Doxil (the liposomal formulation of doxorubicin), DaunoXome is indicated for use in AIDS-related Kaposi s sarcoma and is administered IV at a dose of 40 mg/m every 2 weeks. The pharmacokinetic profiles of Doxil and DaunoXome are similar. [Pg.1804]

See other pages where Daunorubicin citrate liposomal is mentioned: [Pg.584]    [Pg.13]    [Pg.467]    [Pg.187]    [Pg.584]    [Pg.585]    [Pg.584]    [Pg.13]    [Pg.467]    [Pg.187]    [Pg.584]    [Pg.585]    [Pg.358]    [Pg.328]    [Pg.9]    [Pg.217]   
See also in sourсe #XX -- [ Pg.187 ]



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