Round cells

The different applications led to an immense number of configurations and sizes, for example small round cells for hearing aids or large prismatic cells for the lead accumulators used in trucks. Here the great variety of demands has the consequence... 

Another variation of the FRAP technique scans the laser in one dimension across the cell producing a line-scan profile of fluorescence intensity (14). For a round cell whose surface is evenly labeled with a fluorescently conjugated antibody, a line scan typically produces a profile with two peaks of fluorescence, since the laser beam is illuminating more fluorophores at the edges... 

Rat embryo fibroblasts after several days of growth on plates. Normally these cells stop growing as they approach confluency (top frame). Overgrowth of the monolayer by rounded cells is indicative of cellular transformation. Two transformed foci are seen in cells pretreated with both ras- and myc-containing DNA (bottom frame). The transformed cells produced similar transformed cells when repleated and when injected into whole animals produce tumors with a much higher frequency than normal cells. 

Figure 1.3 The round cells are normal red blood cells. The misshapen cell on the left is a sickle cell. Sickle cells clump together and impair blood circulation and the ability of blood to carry oxygen to body tissues.

Figure 1. Polyphenotypic small round cell tumor from the abdomen of a 4-year-old boy. (a) The biopsied material stained weakly for CD99, whereas (b) the excised tumor showed diffuse and strong positivity for the same antigen. The staining procedure used was identical.

The site of pheromone production in male Ca. freemani was found to be the posterior portion of the abdomen (Dowd and Bartelt, 1993). Microscopic examination revealed a male-specific tissue within the abdomen that was composed of very large round cells (100 pm... 

Fig. 11a—c. Different types of cell roundness a polygonal cell, b maximum roundness ceil (r = R), c small roundness cell... 

Fig. 22.2 Subsiding acute viral hepatitis A with lytic loss of hepatocytes and round-cell infiltrates...

Fig. 22.14 Scarred area with fragmented parench)mial islets (- ) after confluent necrosis in the wake of viral hepatitis B (HBsAg+). Localized round-cell infiltration in the remaining parench)Tnal areas (HE)...

Fig. 23.5 Portal (left) and parench)mal (right) round-cell inflammation. Clinical diagnosis Ebola fever...

The transmission of Tryp. cruzi is caused by reduviid bugs, which excrete infectious trypanosomes in their faeces. These enter the body through small skin or mucosal lesions. They cause the South American sleeping sickness , also called Chagas disease (C. Chagas, 1908). In the liver only portal round-cell infiltrates are found. 

Fig. 32.9 Primary biliary cholangitis with cirrhotic transformation. Well-rounded parenchymal residues surrounded by collagenous fibre tissue hardly recognizable bile ducts in the residual round cell-infiltrated portal fields (stages III—IV) (HE)...

---