Rotavirus attenuated strain

Inactivated rabies virus Live attenuated strains of rotavirus... [Pg.398]

Rotavirus vaccines Live attenuated strains of rotavirus Active immunization against rotavirus (causes severe childhood diarrhoea)... [Pg.438]

Rotarix consists of live, attenuated rotavirus strains presented os powder for reconstitution intended for oral administration. [Pg.32]

A good example of the recent and future evolution of viral vaccines and their concomitant issues of technology, complexity and competition, is the rotavirus vaccine. This is of great relevance for the prevention of diarrhea, which is often deadly in developing countries (half a million deaths per year) and has high hospitalization costs in rich countries. After successive failures of monovalent vaccines, multivalent vaccines based on the reshuffling of rotavirus strains comprising the attenuation properties of animal strains with the external capsid of human serotypes were developed. [Pg.454]

Various oral rotavirus vaccines (live attenuated rotavirus vaccines, including rhesus rotavirus and bovine rotavirus strains serotype 1 bovine-human rotavirus reassortant vaccine and both rhesus rotavirus monovalent and tetravalent reassortant vaccines) have been evaluated in clinical trials (SEDA-21, 292). [Pg.3082]

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