Role of Fixative and Embedding Resin in Antigen Retrieval

ROLE OF FIXATIVE AND EMBEDDING RESIN IN ANTIGEN RETRIEVAL 

It is well established that formaldehyde reacts with amino groups on protein side chains (Fig. 7.2), introducing mostly reversible protein crosslinks. Epoxy monomer reacts with the 

On the other hand, in the case of epoxy sections, the resistance in such interfaces is not significantly less than that in tissue proteins, which results in the splitting of protein 

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