Risk reversal definition

Additionally, companies need to say the organization encourages and supports risk taking. The industry has done the reverse for many years. We were averse to risk, which definitely discourages innovation. Just recognizing that a company must not be risk adverse to be successful is an important element. 

An alternate. For those who prefer to deal in terms of acceptable risk, the definition just given is reversible. Thus, acceptable risk is defined as that risk which is tolerated in a given context based on current values of society. 

MAOIs, although effective, are also problematic for routine use in the treatment of BN. First, like the TCAs, MAOIs have a propensity for lowering blood pressure. Additionally, bulimia patients, who are by definition prone to impulsive out of control eating, are not ideal candidates to maintain the strict tyramine-free diet restrictions imposed by MAOIs. Thus, they run a substantial risk of precipitating dangerous hypertensive crises through dietary noncompliance while taking MAOIs. It remains unclear whether the reversible MAOIs such as moclobemide will prove effective in the treatment of BN without the risks associated with other MAOIs. 

First-trimester exposure appears to confer a small but definite increased risk (from a baseline of 0.06% up to 0.7%) of oral cleft in infants (27). However, second-generation effects are infrequent and usually reversible (28), although some doubt remains about the extent of developmental delay in children who have been exposed in utero (27). A review has emphasized that concerns about second-generation effects are mainly theoretical, and has concluded that some agents (for example chlor-diazepoxide) are probably safe during pregnancy and lactation and that others (for example alprazolam) are best avoided (29). 

A value of fc = 3 is considered minimal because it implies definite risks of 7% for false-positive (concluding that the analyte is present when it is absent) and falsenegative (the reverse) decisions. ... 

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