Rift valley fever infection treatment

Other natural PS should be considered for the potential treatment of significant human infections caused by bunyaviruses. The mouse model of Punta Toro virus, a Phlebovirus member of the Bunyaviridae family, is a model for studying the treatment of Rift Valley fever infection. Tragacanthin PS from Astragalus brachycentrus and Astragalus echidnaeformis plants caused reduction in mortality, liver infection scores, liver and spleen virus titers, and serum transaminases in treated mice [131],... 

Interferon alpha has no role in therapy, with the possible exception of Rift Valley fever,34 where fatal hemorrhagic fever has been associated with low interferon responses in experimental animals. However, as an adjunct to ribavirin, exogenous interferon gamma holds promise in treatment of arenaviral infections. 

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