Riboflavin vitamin INDEX

Riboflavin (vitamin B2) was chosen as the number one index vitamin because among the so-called water-soluble vitamins, it is the least soluble in water. If riboflavin is demonstrated to dissolve within the specified time, it is assumed that all other water-soluble vitamins will have also... 

Fermentation industry. Primary metabolites of importance in ihe fermentation field include amino acids, purine nucleotides, vitamins, and organic acids. Specific products include citric acid, riboflavin (vilamin B>). and cubalamin (vilamin B12). Check alphabetical index pertaining lo specific vitamins. Of the secondary metabolites, antibiotics are Ihe mosl... 

Fenech, M., Baghurst, P., Luderer, W., Turner, J., Record, S., Ceppi, M., and Bonassi, S. (2005). Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, beta-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability—Results from a dietary intake and micronucleus index survey in South Australia. Carcinogenesis 26, 991-999. 

In pregnant women, there is a progressive increase in the erythrocyte glutathione reductase activation coefficient (an index of functional riboflavin nutritional status Section 7.5.2), which resolves on parturition despite the daily secretion of 200 to 400 /rg (0.5 to 1 /rmol) of riboflavin into milk. This suggests that the estrogen-induced riboflavin binding protein can sequester the vitamin for fetal uptake at the expense of causing functional deficiency in the mother. 

Pyridoxine phosphate oxidase is a flavoprotein, and activation of the erythrocyte apoenzyme hy riboflavin 5 -phosphate in vitro can he used as an index of riboflavin nutritional status (Section 7.4.3). However, even in riboflavin deficiency, there is sufficient residual activity of pyridoxine phosphate oxidase to permit normal metabolism of vitamin Bg (Lakshmi and Bamji, 1974). Pyridoxine phosphate oxidase is inhibited by its product, pyridoxal phosphate, which binds a specific lysine residue in the enzyme. In the brain, the K, of pyridoxal phosphate is of the order of 2 / mol per L - the same as the brain concentration of free and loosely bound pyridoxal phosphate, suggesting that this inhibition may be a physiologically important mechanism in the control of tissue pyridoxal phosphate (Choi et al., 1987). 

Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin Bg, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, National Academy Press, January 1, 2000. http //www.nap.edu/books/0309065542/html/ index.html. Accessed June 4, 2004. 

Urine. The sensitive determination of riboflavin excreted into urine is of interest because it seems to be a good means for monitoring dietary intake of the vitamin. The flavin content in urine can establish the vitamin B2 status of an individual and it can be used as an index of the relative bioavailability of vitamin... 

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