Rheumatrex

Weekly therapy may be instituted with the Rheumatrex Dose Packs, which are designed to provide doses over a range of 5 to 15 mg administered as a single weekly dose. The dose packs are not recommended for weekly doses greater than 15 mg. Tailor schedules to the individual patient. An initial test dose may be given prior to the regular dosing schedule to detect any extreme sensitivity to adverse effects. Maximal myelosuppression usually occurs in 7 to 10 days. 

Methotrexate (Rheumatrex Dose Pack, TrexaU) Nelarabine (Arranon) Pemetrexed (Alimta) 6-Thioguanine [6-TG] (Tabloid)... 

Methefrexate (Rheumatrex Dose Pack, Trexall) [Antineeplastic/ Antirheumatic (DMARDs), Immunosuppressant/ Antimetabolite] warning Administration only by experienced healthcare provider do not use in women of childbearing age unless absolutely necessary (teratogenic) impaired elimination w/ impaired renal Fxn, ascites, pleural effusion severe myelosuppression if used w/ NSAIDs hepatotox can induce lung Dz ... 

Of the DMARDs, methotrexate (Rheumatrex) is the most widely prescribed. It is indicated for the treatment of rheumatoid arthritis and psoriasis it is also used for psoriatic arthritis, systemic lupus erythematosus, and... 

Methotrexate Rheumatrex, others Oral 2.5-5 mg every 12 hr for total of 3 doses/wk or 10 mg once each week. Can be increased up to a maximum of 20-25 mg/wk. Often effective in halting joint destruction, but long-term use may be limited by toxicity. 

Methotrexate (Folex, Rheumatrex) is an antimetabolite used frequently in the treatment of cancer (see Chapter 36). There is considerable evidence that this drug is also one of the most effective DMARDs.15 76 Methotrexate has been shown to slow the effects of rheumatoid arthritis as evidenced by decreased synovitis, decreased bone erosion, and less narrowing of the joint space.37 The therapeutic effects of methotrexate have also been reported to be equal to, or better than, other DMARDs such as oral gold or azathioprine, and methotrexate may offer an advantage in terms of a rapid onset.68,90 Hence, methotrexate s popularity as a DMARD has increased during the past few years, and this drug is often the first DMARD used to treat rheumatoid arthritis in both adults and children.76... 

Methotrexate Folex, Rheumatrex - Rheumatoid arthritis, psoriasis... 

Methotrexate 2.5-5 mg/d orally (Rheumatrex) 10 mg intrathecally (Folex) once or twice weekly Mucositis, diarrhea, bone marrow depression with leukopenia and thrombocytopenia... 

Trade names Farmitrexat Lantarel Ledertrexate Maxtrex Metex Rheumatrex (Stada) Texate Indications Carcinomas, leukemias, lymphomas, psoriasis, rheumatoid arthritis... 

Methotrexate (amethopterin Rheumatrex, trexall, others) has been used in the treatment of severe, disabling psoriasis in doses of 2.5 mg orally for 5 days, followed by a rest period of at least 2 days, or 10-25 mg intravenously weekly. It also is used intermittently at low dosage to induce remission in rheumatoid arthritis. 

The client is prescribed methotrexate (Rheumatrex), an antineoplastic agent, for psoriasis. Which data should the nurse monitor ... 

The client with rheumatoid arthritis is prescribed the disease-modifying antirheumatic drug (DMARD) methotrexate (Rheumatrex). After 3 days, the client reports that the medication is not working. Which statement is the clinic nurse s best response ... 

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