Retinal vein thrombosis

Women who are lactating or who are or may become pregnant (see Warnings) women with active or a history of venous thromboembolic events, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis hypersensitivity to raloxifene or other constituents of the drug. 

Lake SR, Vernon SA. Emergency contraception and retinal vein thrombosis. Br J Ophthalmol 1999 83(5) 630-1. 

Twenty-five percent ofthrombophilic patients develop thrombosis at unusual sites resulting in cerebral venous thrombosis, mesenteric vein thrombosis, hepatic venous thrombosis, retinal vein thrombosis, purpura fulminans, splenic vein thrombosis, portal vein thrombosis, renal vein thrombosis, or axillary vein thrombosis. The thrombotic disorders may involve inflammatory factors that contribute to the vascular deficit. In addition, embolic events also play a role in the development of these thrombotic complications. 

Common risk factors for developing branch retinal vein thrombosis (BRVT) and central retinal vein thrombosis (CRVT) include increased plasma fibrinogen, diabetes, decreased exercise, hypertension, and hyperviscosity (205). Sickle cell anemia, polycythemia vera, and other proliferative disorders may also lead to this syndrome. 

Central retinal vein thrombosis occurred in a 75-year-old man 20 minutes after the ipsilateral insertion of a 1 % adrenaline-soaked cotton wool stick (15). Unfortunately, his visual acuity did not improve. 

Sensory systems Vision Retinal vein thrombosis has been associated with peginterferon alfa-2b-I-ribavirin in a 46-year-old man with chronic hepatitis C [39" ]. 

Such Dfaz A, Barrueco N, Esteban Alba C, Escobar Rodriguez I. Trombosis venosa retiniana asociada a peginterferdn alfa 2b mas ribavirina en un paciente con hepatitis C crdnica. [Retinal vein thrombosis associated with peginterferon alpha 2b plus ribavirin in a chronic hepatitis C patient.] Farm Hosp 2011 35 93-4. 

A condition in which there are excess macroglobulins in the blood. The high levels of large molecular weight proteins lead to sluggish blood flow and this, in turn, can result in thrombosis in the small blood vessels. Retinal vein thrombosis, cerebral thrombosis and peripheral gangrene (hyperviscosity syndrome) are features. 

After 2 cycles of chemotherapy with capecitabine and oxaliplatin plus bevacizumab, a 50-year-old man with metastatic colon cancer developed central retinal vein thrombosis in the right eye. The temporal relationship between the chemotherapy and iiutial development of symptoms suggests a drug-induced cause with bevacizumab and/or capecitabine the most likely culprit [105 ]. 

Gilbar P, Sorour N. Retinal vein thrombosis in a patient with metastatic colon cancer receiving XELOX chemotherapy combined with bevacizumab pre-hepatic resection. J Oncol Pharm Pract 2012 18(l) 152-4. 

This condition results in inability to remove chylomicrons from the blood. It presents in childhood with eruptive xanthomas, lipaemia retinalis, retinal vein thrombosis, pancreatitis and hepatosplenomegaly... 

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