Purpura fulminans

Ceprotin, can be given. Ceprotin is of course also indicated for patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. 

Twenty-five percent ofthrombophilic patients develop thrombosis at unusual sites resulting in cerebral venous thrombosis, mesenteric vein thrombosis, hepatic venous thrombosis, retinal vein thrombosis, purpura fulminans, splenic vein thrombosis, portal vein thrombosis, renal vein thrombosis, or axillary vein thrombosis. The thrombotic disorders may involve inflammatory factors that contribute to the vascular deficit. In addition, embolic events also play a role in the development of these thrombotic complications. 

Todd PA+, Drugs 35, 244 (1979) Ciucci AG, Rheum Rehab 18 (Suppl 2), 116 Purpura fulminans... 

Protein C Protein C deficiency, purpura fulminans Unknown 3-5 0.06 Liver IPCU, 2PCT PRTC HUMAN... 

EU protein C concentrate anticoagulant Ceprotin Human protein C concentrate purified by MAb Purpura fulminans... 

Skin A 38-year-old man developed purpura fulminans on both breast areas and the abdomen after having taken propylthiouracil for 7 years after withdrawal of propylthiouracil and administration of methylprednisolone he made a full recovery [32 ]. 

Targan et al. (50 ) reported DIC with purpura fulminans one month after starting phenytoin therapy for epilepsy in an 18-year-old female. This was associated with an active vasculitis. The syndrome was successfully treated with heparin and high-dose corticosteroids. 

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