Respiratory system catecholamines

Respiratory system The presence of P receptors in bronchial smooth muscle causes relaxation and activation of these receptors by P2 agonists cause bronchodilatation. Among catecholamines, adrenaline and isoprenaline are potent bronchodilators due to its P2 action but not noradrenaline. 

Thin layer chromatographic analysis is also highly applicable to the determination of aromatic organic acids.In human organisms, aromatic acids are synthesized as metabolites in intoxication by toluene, xylene, and ethyl benzene. These compounds are easily absorbed through the skin or respiratory system, and are oxidized to aromatic acids. The separation, identification, and quantitative analyses of aromatic acids are also necessary because they appear as semiproducts of the biosynthesis of aromatic amino acids in plants (phenolic acids), and metabolites of numerous toxic substances, drugs, and catecholamines. Polar adsorbents and polar-... 

In stroke patients presenting to the ED, the first goal of treatment is immediate cardiac and respiratory stabilization. The systemic blood pressure is most often elevated in the setting of an acute stroke as the result of a catecholamine surge, and if the patient is hypotensive, the clinician should consider a concomitant cardiac process, such as myocardial infarction (MI), congestive heart failure (CHF), or pulmonary embolism (PE). 

P-Adrenergic receptors ((i-ARs) are members of the superfamily of G protein-coupled receptors that are stimulated by the catecholamines epinephrine and norepinephine (1). As part of the sympathetic nervous system, P-ARs have important roles in cardiovascular, respiratory, metabolic, central nervous system, and reproductive functions. Mice lacking one or more of the three p-AR subtype genes (P, p2, and p3) have been generated to elucidate the physiological role of individual subtypes. Moreover, cells and tissues extracted from these mice have been utilized as tools to understand the molecular and cellular basis of subtype-specific receptor function. These studies are summarized in this chapter. 

A. Toluene and xylene cause generalized central nervous system depression. Like other aromatic hydrocarbons, they may sensitize the myocardium to the arrhythmogenic effects of catecholamines. They are mild mucous membrane irritants affecting the eyes and respiratory and gastrointestinal tracts. 

Liver Although chloroform is no longer in use as a volatile anesthetic agent, cases of occupational exposure as well as intentional inhalation and ingestion still present to clinicians. Chloroform was withdrawn from clinical use because it can cause nervous system depression, anoxia secondary to respiratory depression and airway obstruction, cardiac dysrhythmias potentiated by circulating catecholamines, and hepato-toxicity, which is thought to be secondary to oxidative injury caused by free radicals. 

---