Respiratory pneumonia, glucocorticoids

There have been no reports of an increased frequency of lower respiratory tract infections. However, patients with aspiration of gastric material who were treated with glucocorticoids did not have improved survival but had a higher incidence of pneumonia (SED-12, 982). 

A 33-year-old man who had taken sertraline 50 mg/day and risperidone 2 mg/day for 3 years developed acute respiratory failure. A lung biopsy confirmed pulmonary fibrosis with eosinophilic and organizing pneumonia. He recovered on withdrawal of both agents and glucocorticoid therapy. 

Respiratory Three cases of interstitial pneumonia have been described in Japanese patients during treatment with bepridil. In one case, exertional dyspnea developed over 8 months and transbronchial lung biopsy specimens showed moderate lymphocytic infiltration glucocorticoid therapy led to resolution in 3 weeks [48 ]. The other two patients developed pneumonia after 20 and 60 days one required glucocorticoid treatment and the other was discharged having improved after bepridil withdrawal [49 ]. 

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