Resetting strength

Figure 34.18 Myosin motion along actin. A myosin head (yellow) in the ADP form is bound to an actin filament (blue). The exchange of ADP for ATP results in (1) the release of myosin from actin and (2) substantial reorientation of the lever arm of myosin. The hydrolysis of ATP (3) allows the myosin head to rebind at a site displaced along the actin filament (4). The release of P, (5 accompanying this binding increases the strength of the interaction between myosin and actin and resets the orientation of the lever arm.

To obtain the proper initial geostatic stress state of the slope, static calculation is required before the dynamic analysis (Itasca Consulting Group, 1999). Two procedures are followed in the static calculation (a) set relevant mechanical parameters and take elastic model as material constitutive model, and then make the slope model balanced in gravity field (b) take Mohr-Coulomb model as the material constitutive model (Yan et al., 2011) and reset cohesion and tensile strength to their initial value, and then rebalance the model. This is just the slope model on which the dynamic load will be applied. The contour plot of initial vertical geostatic stresses in the slope (Figure 3) reflects the vertical stress state in which no dynamic load is applied on the slope. 

A plot of the new phase 0 as a function of the initial phase 0o at fixed pulse strength s constitutes the phase-resetting curve. The system will be more sensitive to perturbation at some points on its cycle than at others, and this is the information that is contained in the resetting curve. A set of curves at different values of s can be a valuable guide to the nature of an oscillator. Biologists have often exploited this technique in their studies of both neurons and circadian rhythms. 

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