Phase-resetting curve

B. Ermentrout, Type I membranes, phase resetting curves, and synchrony. Neural Computation 8 (1996) 979-1001... 

A plot of the new phase 0 as a function of the initial phase 0o at fixed pulse strength s constitutes the phase-resetting curve. The system will be more sensitive to perturbation at some points on its cycle than at others, and this is the information that is contained in the resetting curve. A set of curves at different values of s can be a valuable guide to the nature of an oscillator. Biologists have often exploited this technique in their studies of both neurons and circadian rhythms. 

Mobile phase recycled but detector not adjusted. 10. Detector (UV) not set at absorbance maximum but at slope of curve. 9. Reset baseline. Use new materials when dynamic range of detector is exceeded. 10. Change wavelength to UV absorbance maximum. 

---