Research tradition

Toxicity Amelioration. Cancer researchers traditionally have not focused their attention on the question of toxicity amehoration. This is partiy attributed to the lack of predictive animal models for human toxicities. For example, the preclinical rat model, used as a predictor of myelosuppression, has failed to predict myelosuppression in humans in clinical trials. In addition, reduction of one toxicity may result in the emergence of another, more serious problem. Research efforts to address the problem of toxicity amelioration has progressed in several directions. The three most prominent areas are analogue synthesis, chemoprotection, and dmg targeting. 

Bartholomew, J.R, (1987) The Formation of Science in Japan Building a Research Tradition (Yale University Press, New Haven and London) pp, 63, 186. 

McKernan, J. (1988). The countenance of curriculum action research Traditional, collaborative, and emancipatory-critical conceptions. Journal of Curriculum and Supervision, 5(3), 173-200. 

Frederic Lawrence Holmes, Lavoisier and the Chemistry of Life An Exploration of Scien-tific Creativity (Madison University of Wisconsin Press, Antoine Lavoisier The Next Crucial Year (Princeton Princeton University Press, 1998). See also Holmes, Lavoisier s Conceptual Passage, in Arthur Donovan, ed., The Chemical Revolution. Essays in Reinterpretation, Osiris 4 (1988) 82-92. This special issue of Osiris also contains C.E. Perrin, Research Traditions, Lavoisier and the Chemical Revolution, 53-81. 

Carleton E. Perrin, one of the most productive of Lavoisier scholars, provided a thorough account of the phlogiston chemistry that dominated French chemistry before Lavoisier Research Traditions, Lavoisier and the Chemical Revolution, Osiris 4 (1988) 53-81. In the same issue of Osiris, J.B. Gough offered a unique but dubious view of the importance of Stahls phlogistic theo 7+ Lavoisier and the Fulfillment of the Stahlian Revolution, Osiris 4 (1988) 15-33. 

Perrin, Carleton E. Research Traditions, Lavoisier and the Chemical Revolution. Osiris 4 (1988) 53-81. 

The epigenetics research tradition in human diseases has been rather weak thus far. Epigenetic factors have been investigated only when their role was evident from epidemological, cytogenetic, or other type of studies. The best example is the rare pediatric diseases that are often caused by... 

However, comparative studies, including cross-cultural analysis of news coverage, are common within the field of political communication. For an overview of this research tradition see Tjernstrom (2001). 

C. E. Perrin, Research Traditions, Lavoisier, and the Chemical Revolution, Osiris [2] 4, 1988, 53-81 John G. McEvoy, Continuity and Discontinuity in the Chemical Revolution, ibid., 195-213. 

Perrin, C. E. Of Theory Shifts and Industrial Innovations The Relations of J. A. C. Chaptal and A. L. Lavoisier. Annals of Science 43,1986, 511-542. Perrin, C. E. Revolution or Reform The Chemical Revolution and Eighteenth Century Concept of Scientific Change. History of Science 15, 1987, 395-423. Perrin, C. E. Research Tradition, Lavoisier, and the Chemical Revolution. Osiris [2] 4, 1988, 53-81. 

Moss, Pamela A. 1996. Enlarging the dialogue in educational measurement Voices from interpretive research traditions. Educational Researcher 25 (1) 20-28, 43. 

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